Mitral valve prolapse

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Heart, section through the middle

Heart valve surgery - series

Mitral valve prolapse

Mitral valve prolapse is a heart problem in which the valve that separates the left upper and lower chambers of the heart does not open and close properly.

Barlow's syndrome; Floppy mitral valve; Myxomatous mitral valve; Billowing mitral valve; Systolic click-murmur syndrome; Prolapsing mitral leaflet syndrome

The heart's mitral valve helps blood on the left side of the heart flow in one direction. It closes to keep blood from moving backwards when the heart beats (contracts).

If the valve does not open and close properly it is called mitral valve prolapse. It can be caused by many different things. In most cases, it is harmless and patients usually do not know they have the problem. In a small number of cases, it can cause blood to leak backwards (severe mitral regurgitation). This needs to be treated with surgery.

Some forms of mitral valve prolapse seem to be passed down through families (inherited). Mitral valve prolapse has been associated with Marfan syndrome (a disorder present from birth) and Graves disease.

Many people with mitral valve prolapse are thin women who may have minor chest wall deformities, scoliosis, or other disorders.

Some people with mitral valve prolapse may also have a hole in their heart called an atrial septal defect.

Review Date: 07/17/2006
Reviewed By: Glenn Gandelman, MD, MPH, Assistant Clinical Professor of Medicine, New York Medical College, Valhalla, NY. Review provided by VeriMed Healthcare Network.