Idiopathic pulmonary fibrosis

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Clubbing

Respiratory system

Spirometry

Idiopathic pulmonary fibrosis involves scarring or thickening of tissues deep in the lung without a known cause.

Idiopathic diffuse interstitial pulmonary fibrosis; IPF; Pulmonary fibrosis; Cryptogenic fibrosing alveolitis; CFA; Fibrosing alveolitis; Usual interstitial pneumonitis; UIP

Idiopathic pulmonary fibrosis is a disease of the lower respiratory tract that damages the air sacs (alveoli) and leads to reduced transfer of oxygen to the blood. It causes widespread scarring of the lung.

The condition is believed to result from an inflammatory response to an unknown agent -- "idiopathic" means no cause can be found. The disease occurs most often in people between 50 and 70 years old.

Review Date: 05/03/2006
Reviewed By: David A. Kaufman, M.D., Assistant Professor, Division of Pulmonary, Critical Care & Sleep Medicine, Mount Sinai School of Medicine, New York, NY. Review provided by VeriMed Healthcare Network.